In this presentation, Marina Serper, MD, offers a comprehensive examination of the pathophysiology, prophylaxis and management of bleeding esophageal varices. Dr. Serper reviews the variety of therapies available for varices, including transjugular intrahepatic portosystemic shunts (TIPS), balloonoccluded retrograde transvenous obliteration (BRTO) and the investigative treatment cyanoacrylate injection.