Patellofemoral pain from cartilage degeneration can be caused by predisposition, muscular weakness or congenital anatomic malalignment. In this video, 2017 Penn Center for Precision Medicine Accelerator Fund recipient Miltiadis Zgonis, MD, explains the development of an approach grounded in precision medicine that identifies early cartilage degeneration at the molecular level to prevent or avoid later structural failure at the knee. Dr. Zgonis is an Assistant Professor of Orthopaedic Surgery a Penn Medicine.
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