In this fast-paced presentation, Charu Aggarwal, MD, of the Abramson Cancer Center at Penn Medicine, examines the findings of clinical reports from ASCO 2016 with regard to small cell and non-small cell lung cancer therapy. Dr. Aggarwal's review includes a discussion of recent advances for relapsed/refractory ES-SCLC, adjuvant chemotherapy and immunotherapy for NSCLC, and a discussion of ALK positive NSCLC.